Ceritinib dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15656A-5 mg |
| CAS # | 1380575-43-8 |
| Pricing | 5 mg, USD $50.0 |
| Synonyms | LDK378 dihydrochloride |
| MWt | 631.06 |
| Formula | C₂₈H₃₈Cl₃N₅O₃S |
| Biological Activity | Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride (LDK378 dihydrochloride) shows great antitumor potency[1][2]. |
| Purity | 99.83% |