BRD5648
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-116830B-10 mg |
| CAS # | 2056261-42-6 |
| Pricing | 10 mg, USD $1050.0 |
| Biological Activity | BRD5648 ((R)-BRD0705) is a negative control of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML)[1][2]. |
| Synonyms | (R)-BRD0705 |
| MWt | 321.42 |
| Formula | C₂₀H₂₃N₃O |