SAR405
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12481-5 mg |
| CAS # | 1523406-39-4 |
| Pricing | 5 mg, USD $130.0 |
| Biological Activity | SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity[1][2]. |
| Purity | 99.52% |
| MWt | 443.85 |
| Formula | C₁₉H₂₁ClF₃N₅O₂ |