R59949
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108355-5 mg |
| CAS # | 120166-69-0 |
| Pricing | 5 mg, USD $270.0 |
| Biological Activity | R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK α and γ and moderately attenuates the activity of type II DGK θ and κ. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol[1][2][3]. |
| Purity | ≥99.0% |
| MWt | 489.58 |
| Formula | C₂₈H₂₅F₂N₃OS |