Fasudil Hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10341-200 mg |
| CAS # | 105628-07-7 |
| Pricing | 200 mg, USD $84.0 |
| Biological Activity | Fasudil Hydrochloride (HA-1077 Hydrochloride; AT877 Hydrochloride), is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively[1]. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator[2]. |
| Synonyms | HA-1077 Hydrochloride; AT-877 Hydrochloride |
| MWt | 327.83 |
| Formula | C₁₄H₁₈ClN₃O₂S |