P-Selectin Glycoprotein Ligand 1 (SELPLG) Antibody
SELPLG Antibody is a Rabbit Polyclonal antibody against SELPLG. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytesAs such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectinsThis protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activityAberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune responseAlternate splicing results in multiple transcript variants.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx117135-100UL |
| Pricing | 100 µl USD $522.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | ELISA, WB, IHC |
| UniProt Primary AC | Q14242 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |