Ubiquitin Carboxyl-Terminal Hydrolase BAP1 (BAP1) Antibody
BAP1 Antibody is a Rabbit Polyclonal antibody against BAP1. This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
| Supplier | Abbexa Ltd. |
|---|---|
| Product # | abx005012-200UL |
| Pricing | 200 µl USD $696.0 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Tested Applications | WB, IHC, IF/ICC |
| UniProt Primary AC | Q92560 |
| Dry Ice | No |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |