N-Desmethyltamoxifen
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-129099 |
| CAS # | 31750-48-8 |
| Pricing | inquire |
| Biological Activity | N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3]. |
| MWt | 357.49 |
| Formula | C₂₅H₂₇NO |