| Supplier |
Creative Peptides |
| Product # |
R1808 |
| CAS # |
103429-31-8 |
| Pricing |
Inquire
|
| Synonyms |
CTOP, (Tyr3,Orn5,Pen7)-Octreotate amide
|
| MolecularFormula |
C50H67N11O11S2
|
| MolecularWeight |
1062.26
|
| Sequence |
- One Letter Code: FCYW{Orn}T{Pen}T-NH2 (Disulfide bridge:Cys2-Pen7)
- Three Letter Code: Phe-Cys-Tyr-Trp-{Orn}-Thr-{Pen}-Thr-NH2 (Disulfide bridge:Cys2-Pen7)
|
| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
| Explanation |
CTOP is a peptide that acts as a μ-opioid receptor antagonist.
|
| Solubility |
Soluble to 1 mg/ml in water
|
| BiologicalActivity |
Potent and selective μ opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for μ and δ receptors respectively). Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a μ receptor independent mechanism.
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