PF-06843195
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131972-5 mg |
| CAS # | 2067281-51-8 |
| Pricing | 5 mg, USD $500.0 |
| Biological Activity | PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy[1]. |
| MWt | 498.46 |
| Formula | C₂₀H₂₅F₃N₈O₄ |