PFK-158
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12203-5 mg |
| CAS # | 1462249-75-7 |
| Pricing | 5 mg, USD $60.0 |
| Biological Activity | PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria[1][2][3]. |
| Purity | 98.09% |
| MWt | 328.29 |
| Formula | C₁₈H₁₁F₃N₂O |