UMI-77
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18628-100 mg |
| CAS # | 518303-20-3 |
| Pricing | 100 mg, USD $650.0 |
| Biological Activity | UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members. |
| MWt | 468.34 |
| Formula | C₁₈H₁₄BrNO₅S₂ |