Selumetinib
Supplier | MedChemExpress |
---|---|
Product # | HY-50706-10 mM * 1 mL |
CAS # | 606143-52-6 |
Pricing | 10 mM * 1 mL, USD $79.0 |
Synonyms | AZD6244; ARRY-142886 |
MWt | 457.68 |
Formula | C₁₇H₁₅BrClFN₄O₃ |
Biological Activity | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. |
Purity | 99.87% |