Recombinant Human Anti-H3N2 HA Antibody (F005-126)
Recombinant Human Antibody (F005-126) is capable of binding to H3N2 HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-H3N2 HA mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-H3N2 HA proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. F005-126 has the ability to prevent low-pH-induced conformational changes in hemagglutinin. The newly identified conserved epitope, including the glycan, should be immunogenic in humans and may induce production of broadly neutralizing antibodies against H3 viruses.
Supplier | Creative Biolabs |
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Product # | PABC-160 |
Pricing | Inquiry |
Host | Human |
Target | H3N2 HA |
Species Reactivity | H3N2 |
Type | IgG |
Applications | Can be useful in applications such as: Neutralization, Enzyme-linked Immunosorbent Assay, Flow Cytometry |
Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |