CMC2.24
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-120793-10 mM * 1 mL |
| CAS # | 1255639-43-0 |
| Pricing | 10 mM * 1 mL, USD $330.0 |
| Biological Activity | CMC2.24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 μM. CMC2.24 alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis[1][2][3]. |
| Synonyms | TRB-N0224 |
| MWt | 427.45 |
| Formula | C₂₆H₂₁NO₅ |