LG100268
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15340-10 mg |
| CAS # | 153559-76-3 |
| Pricing | 10 mg, USD $160.0 |
| Synonyms | LG268 |
| MWt | 363.49 |
| Formula | C₂₄H₂₉NO₂ |
| Biological Activity | LG100268 (LG268) is a potent, selective and orally active retinoid X receptor (RXR) agonist with EC50 values of 4 nM, 3 nM, and 4 nM for RXR-α, RXR-β, and RXR-γ, respectively[1]. LG100268 displays >1000-fold selectivity for RXR over RAR, the Ki values are 3.4 nM, 6.2 nM and 9.2 nM for RXR-α, RXR-β, and RXR-γ, respectively[2]. LG100268 activates RXR homodimers to induce transcriptional activation. LG100268 can be used for the study of lung carcinogenesisy[3]. |
| Purity | 99.22% |