NF449 octasodium
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112461A-1 mg |
| CAS # | 627034-85-9 |
| Pricing | 1 mg, USD $280.0 |
| Biological Activity | NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gsα-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[γS] binding to Gsα-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of β-adrenergic receptors to Gs[1][2]. |
| Purity | ≥99.0% |
| MWt | 1505.09 |
| Formula | C₄₁H₂₄N₆Na₈O₂₉S₈ |