7-Chlorokynurenic acid
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100811-10 mM * 1 mL |
| CAS # | 18000-24-3 |
| Pricing | 10 mM * 1 mL, USD $77.0 |
| Synonyms | 7-CKA |
| MWt | 223.61 |
| Formula | C₁₀H₆ClNO₃ |
| Biological Activity | 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery[1][2]. |
| Purity | 99.71% |