Benzamil hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-B1546A-10 mM * 1 mL |
| CAS # | 161804-20-2 |
| Pricing | 10 mM * 1 mL, USD $66.0 |
| Synonyms | Benzylamiloride hydrochloride |
| MWt | 356.21 |
| Formula | C₁₃H₁₅Cl₂N₇O |
| Biological Activity | Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM[1][2][3]. |
| Purity | 99.60% |