isocitrate dehydrogenase (NAD+)
Requires Mn2+ or Mg2+ for activity. Unlike EC 1.1.1.42, isocitrate dehydrogenase (NADP+), oxalosuccinate cannot be used as a substrate. In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD+-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP+-linked enzyme that is found in both mitochondria and cytoplasm. The enzyme from some species can also use NADP+ but much more slowly.
| Supplier | Creative Enzymes |
|---|---|
| Product # | EXWM-0326 |
| Pricing | 100 ug, contact supplier for pricing |
| CAS | 9001-58-5 |