5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite

5'-O-DMT-2'-O-MOE-5-Me-rC(Bz)-3'-((2-cyanoethoxy)(diisopropylamino)phosphoramidite)-ethyl-diisopropylphosphoramidite, employed in oligonucleotide synthesis, features a 5'-O-DMT protecting group and contains a diisopropylamino group for coupling with the next nucleotide. The nucleoside unit is 5-methylcytidine (5-Me-rC), modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. Additionally, it contains a phosphoramidite group for solid-phase synthesis. The presence of a cyanoethoxy group at the 3'-end facilitates efficient coupling reactions during synthesis. This compound is valuable in generating modified RNA sequences with enhanced stability and target specificity, suitable for various research applications including RNA-based therapeutics and gene editing.

• Supplier: BOC Sciences
• Product #: BRP-00605
• Molecular Weight: 1113.24
• Molecular Formula: C58H78N6O12P2