Phenoxodiol
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13721-10 mM * 1 mL |
| CAS # | 81267-65-4 |
| Pricing | 10 mM * 1 mL, USD $159.0 |
| Synonyms | Idronoxil; Dehydroequol; Haginin E |
| MWt | 240.25 |
| Formula | C₁₅H₁₂O₃ |
| Biological Activity | Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner[1][2]. |
| Purity | ≥98.0% |