G907
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-125176-50 mg |
| CAS # | 2244035-16-1 |
| Pricing | 50 mg, USD $3200.0 |
| Biological Activity | G907 is a selective small-molecule antagonist of ATP-binding cassette (ABC) transporter, MsbA. It inhibits purified E. coli MsbA in amphipols with an IC50 of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket. Bactericidal activity[1]. |
| Purity | 98.34% |
| MWt | 433.93 |
| Formula | C₂₆H₂₄ClNO₃ |