TAK-960
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15160-10 mg |
| CAS # | 1137868-52-0 |
| Pricing | 10 mg, USD $216.0 |
| Biological Activity | TAK-960 is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts[1]. |
| MWt | 561.6 |
| Formula | C₂₇H₃₄F₃N₇O₃ |