GNF4877

Supplier MedChemExpress
Product # HY-129492-10 mg
CAS # 2041073-22-5
Pricing 10 mg, USD $1100.0
Biological Activity GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (EC50 of 0.66 μM for mouse β (R7T1) cells)[1].
Purity 98.85%
MWt 494.52
Formula C₂₅H₂₇FN₆O₄
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