GNF4877
Supplier | MedChemExpress |
---|---|
Product # | HY-129492-10 mg |
CAS # | 2041073-22-5 |
Pricing | 10 mg, USD $1100.0 |
Biological Activity | GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (EC50 of 0.66 μM for mouse β (R7T1) cells)[1]. |
Purity | 98.85% |
MWt | 494.52 |
Formula | C₂₅H₂₇FN₆O₄ |