MK-5108 (VX-689)

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MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.

Supplier	Selleck Chemicals
Product #	S2770
Sku #	S2770-10mM/1mL
Pricing	10mM/1mL, $500.00

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