Lopinavir
Supplier | MedChemExpress |
---|---|
Product # | HY-14588-50 mg |
CAS # | 192725-17-0 |
Pricing | 50 mg, USD $60.0 |
Synonyms | ABT-378 |
MWt | 628.8 |
Formula | C₃₇H₄₈N₄O₅ |
Biological Activity | Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM[3]. |
Purity | 99.97% |