CSRM617
Supplier | MedChemExpress |
---|---|
Product # | HY-122611 |
CAS # | 787504-88-5 |
Pricing | inquire |
Biological Activity | CSRM617 is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 is well tolerated in the prostate cancer mouse model[1] |
MWt | 255.23 |
Formula | C₁₀H₁₃N₃O₅ |