MK-2206 2HCl
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2.
Supplier | Selleck Chemicals |
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Product # | S1078 |
Sku # | S1078-100mg |
Pricing | 100mg, $790.00 |
Citations for this product:
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bioRxiv - Physiology 2023Quote: ... or the Akt inhibitor MK-2207 (Cat#S1078, Selleck Chemicals LLC) at concentrations stated in the figure legends.
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bioRxiv - Immunology 2023Quote: ... MK-2206 (Selleck chemicals, #S1078), TAK-242 (Sigma-Aldrich ...
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bioRxiv - Cancer Biology 2023Quote: ... AKT-inhibitor MK-2206 2HCl (Selleck Chemicals #S1078), and VPS34-IN1 (Cayman Chemical #17392 ...