T6167923
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-19744-5 mg |
| CAS # | 2437475-16-4 |
| Pricing | 5 mg, USD $560.0 |
| Biological Activity | T6167923 is a potent and selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with an 50 of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively[1]. |
| Purity | 99.42% |
| MWt | 458.39 |
| Formula | C₁₇H₂₀BrN₃O₃S₂ |