| Supplier |
Creative Peptides |
| Product # |
C15019 |
| Pricing |
Inquire
|
| MolecularWeight |
2012.4
|
| Sequence |
- One Letter Code: GAHWQFNALTVRGGGS-K(Biotin)
- Three Letter Code: H-Gly-Ala-His-Trp-Gln-Phe-Asn-Ala-Leu-Thr-Val-Arg-Gly-Gly-Gly-Ser-Lys(Biotin)-OH
|
| Storage |
-20°C
|
| Explanation |
This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
|
| Reference |
- 1. Mahaffey, C. and ME Mummert. J Immunol 179, 8191 (2007);
- 2. Mummert, M. et al. J Exp Med 192, 769 (2000).
|