Rocaglamide
Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-κB activity. Rocaglamide exhibits anti-tumor activity.
Supplier | Selleck Chemicals |
---|---|
Product # | S7428 |
Sku # | S7428-10mM/1mL |
Pricing | 10mM/1mL, $890.00 |