Tradipitant
Tradipitant, also known as VLY-686 and LY686017, is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models. LY686017 may be a possible therapy for alcoholism. LY686017 can be also served as a suitable chemical platform for future imaging ligand development.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD427 |
| CAS # | 622370-35-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | Tradipitant; LY686017; LY 686017; LY686017; VLY 686; VLY686; VLY686. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C28H16ClF6N5O |
| Exact Mass | 587.09476 |
| Molecular Weight | 587.9 |
| Elemental Analysis | C, 57.20; H, 2.74; Cl, 6.03; F, 19.39; N, 11.91; O, 2.72 |
| IUPAC/Chemical Name | (2-(1-(3,5-bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone |
| InChi Key | CAVRKWRKTNINFF-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C28H16ClF6N5O/c29-22-6-2-1-4-20(22)26(41)21-5-3-9-37-23(21)24-25(17-7-10-36-11-8-17)40(39-38-24)15-16-12-18(27(30,31)32)14-19(13-16)28(33,34)35/h1-14H,15H2 |
| SMILES Code | O=C(C1=CC=CN=C1C2=C(C3=CC=NC=C3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=N2)C5=CC=CC=C5Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |