BT2
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-114855-10 mM * 1 mL |
| CAS # | 34576-94-8 |
| Pricing | 10 mM * 1 mL, USD $55.0 |
| Biological Activity | BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2]. |
| Purity | 99.56% |
| MWt | 247.1 |
| Formula | C₉H₄Cl₂O₂S |