Nevanimibe
Supplier | MedChemExpress |
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Product # | HY-100399 |
CAS # | 133825-80-6 |
Pricing | inquire |
Biological Activity | Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer[1]. |
Synonyms | PD-132301; ATR-101 |
MWt | 421.62 |
Formula | C₂₇H₃₉N₃O |