Nevanimibe

Supplier MedChemExpress
Product # HY-100399
CAS # 133825-80-6
Pricing inquire
Biological Activity Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer[1].
Synonyms PD-132301; ATR-101
MWt 421.62
Formula C₂₇H₃₉N₃O
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