Moclobemide-d4
Moclobemide-d4 is intended for use as an internal standard for the quantification of moclobemide by GC- or LC-MS. Moclobemide is a reversible inhibitor of monoamine oxidase A (MAO-A; Ki = 0.005 µM). It is selective for MAO-A over MAO-B (Ki = 1.08 µM). Chronic administration of moclobemide (15 mg/kg) decreases immobility in the forced swim test in rats. It increases time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic-like activity, when administered chronically at a dose of 20 mg/kg. Formulations containing moclobemide have been used in the treatment of major depressive disorder, bipolar disorder, and social anxiety.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD582 |
| CAS # | unknown |
| Pricing | Customizable size, Inquiry |
| Synonym | Moclobemide-d4; Moclobemide d4; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C13H13D4ClN2O2 |
| Exact Mass | 272.123 |
| Molecular Weight | 272.7654 |
| Elemental Analysis | C, 57.24; H, 7.76; Cl, 13.00; N, 10.27; O, 11.73 |
| IUPAC/Chemical Name | 4-chloro-N-(2-morpholinoethyl)benzamide-2,3,5,6-d4 |
| InChi Key | YHXISWVBGDMDLQ-RHQRLBAQSA-N |
| InChi Code | InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)/i1D,2D,3D,4D |
| SMILES Code | ClC1=C(C([2H])=C(C([2H])=C1[2H])C(NCCN2CCOCC2)=O)[2H] |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Anxiety |
| Availability | 2 Weeks |