SB-612111 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-18617 |
| CAS # | 371980-94-8 |
| Pricing | inquire |
| Biological Activity | SB-612111 hydrochloride is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 hydrochloride exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model[1]. |
| MWt | 454.86 |
| Formula | C₂₄H₃₀Cl₃NO |