Nirogacestat
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15185-100 mg |
| CAS # | 1290543-63-3 |
| Pricing | 100 mg, USD $1000.0 |
| Synonyms | PF-3084014; PF-03084014 |
| MWt | 489.64 |
| Formula | C₂₇H₄₁F₂N₅O |
| Biological Activity | Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1]. |
| Purity | 98.23% |