Transforming Growth Factor Beta Receptor 2 (TGFBR2) Antibody
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Supplier | Abbexa Ltd. |
---|---|
Product # | abx026476-400UL |
Pricing | 400 µl USD $601.75 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB, IHC, IF/ICC |
UniProt Primary AC | P37173 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |