Transforming Growth Factor Beta Receptor 2 (TGFBR2) Antibody

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
Supplier Abbexa Ltd.
Product # abx026476-400UL
Pricing 400 µl USD $601.75
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications ELISA, WB, IHC, IF/ICC
UniProt Primary AC P37173
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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