5-O-Demethylnobiletin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N1942-10 mg |
| CAS # | 2174-59-6 |
| Pricing | 10 mg, USD $269.0 |
| Synonyms | 5-Demethylnobiletin |
| MWt | 388.37 |
| Formula | C₂₀H₂₀O₈ |
| Biological Activity | 5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Sideritis tragoriganum, is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM[1]. |
| Purity | ≥99.0% |