Pyridone 6
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-14435-10 mM * 1 mL |
| CAS # | 457081-03-7 |
| Pricing | 10 mM * 1 mL, USD $245.0 |
| Biological Activity | Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases. |
| Purity | 98.84% |
| MWt | 309.34 |
| Formula | C₁₈H₁₆FN₃O |