Human Anti-ITGA2B Recombinant Antibody (clone RUC-2)
Recombinant Human Antibody (RUC-2) is capable of binding to ITGA2B, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ITGA2B mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ITGA2B proteins mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody inhibits ligand binding by a mechanism different from that of all other α(IIb)β(3) antagonists and may offer advantages as a therapeutic agent.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-747 |
| Pricing | Inquiry |
| Host | Human |
| Target | ITGA2B |
| Species Reactivity | Human |
| Type | Human IgG |
| Applications | Block |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |