Gap19
Supplier | MedChemExpress |
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Product # | HY-P1136 |
CAS # | 1507930-57-5 |
Pricing | inquire |
Biological Activity | Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial[1][2]. |
MWt | 1161.44 |
Formula | C₅₅H₉₆N₁₄O₁₃ |