Lexibulin
Supplier | MedChemExpress |
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Product # | HY-10498-50 mg |
CAS # | 917111-44-5 |
Pricing | 50 mg, USD $732.0 |
Synonyms | CYT-997 |
MWt | 434.53 |
Formula | C₂₄H₃₀N₆O₂ |
Biological Activity | Lexibulin (CYT-997) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo[1][2]. Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells[3]. |
Purity | 98.08% |