Recombinant Anti-TLR2 Intrabody [Tat]
Recombinant anti-TLR2 intrabody in fusion with HIV Tat works within cells towards TLR2, expressed in CHO cells. Intracellular antibodiess expressed and retained inside the endoplasmatic reticulum (ER-intrabodies) are applied to block translocation of secreted and cell surface molecules from the ER to the cell surface resulting in functional inhibition of the target protein. since cell activation via TLR2 and other pattern recognition receptors (PRRs) contributes to sepsis pathology and chronic inflammation both relying on overamplification of an immune response.
| Supplier | Creative Biolabs |
|---|---|
| Product # | IAB-B030(T) |
| Pricing | Inquiry |
| Host | murine |
| Target | TLR2 |
| Type | scFv-Tat |
| Applications | Used for immunoassay techniques such as: Immunofluorescence; Flow Cytometry; Western blot; Functional studies |
| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples. |