Pacritinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-16379-10 mg |
| CAS # | 937272-79-2 |
| Pricing | 10 mg, USD $110.0 |
| Synonyms | SB1518 |
| MWt | 472.58 |
| Formula | C₂₈H₃₂N₄O₃ |
| Biological Activity | Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). Pacritinib also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). |
| Purity | 99.93% |