Hexokinase 1 (HK1) Antibody
The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate.Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK).Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids.Glucokinase lacks the N-terminal hydrophobic cluster.The hydrophobic cluster is thought to be necessary for membrane binding.This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases.HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.
Supplier | Abbexa Ltd. |
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Product # | abx015885-100UL |
Pricing | 100 µl USD $420.5 |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Host | Mouse |
Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
UniProt Primary AC | P19367 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |