Samotolisib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-12513-50 mg |
| CAS # | 1386874-06-1 |
| Pricing | 50 mg, USD $550.0 |
| Synonyms | LY3023414 |
| MWt | 406.48 |
| Formula | C₂₃H₂₆N₄O₃ |
| Biological Activity | Samotolisib (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, DNA-PK and mTOR, respectively. Samotolisib potently inhibits mTORC1/2 at low nanomolar concentrations[1][2]. |
| Purity | 99.77% |