Embelin

Supplier MedChemExpress
Product # HY-17473-10 mg
CAS # 550-24-3
Pricing 10 mg, USD $66.0
Synonyms Embelic acid; Emberine; NSC 91874
MWt 294.39
Formula C₁₇H₂₆O₄
Biological Activity Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor (IC50=4.1 μM), inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells[1][2][3].
Purity 98.75%
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