| Supplier |
Creative Peptides |
| Product # |
X21179 |
| Pricing |
Inquire
|
| MolecularWeight |
778
|
| Sequence |
- One Letter Code: 2-Furoyl-LIGRLO-NH2
- Three Letter Code: 2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2
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| Storage |
-20°C
|
| Explanation |
The peptide 2-furoyl-LIGRLO-NH2 showed higher potency and receptor selectivity for in vitro assays than other PAR-2-activating peptides. 2-Furoyl-LIGRLO-NH2 peptide was equally or more potent than SLIGRL-NH2 for increasing intracellular calcium in cultured human and rat PAR-2-expressing cells and significantly more potent than SLIGRL-NH2 in assays of tissue PAR-2 activity.
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| Reference |
McGuire, JJ. et al. J Pharmacol Exp Ther 309, 1124 (2004).
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